The use of antibiotics is often considered among the most important advances in the treatment of human disease. Unfortunately, though, bacteria are finding ways to make a comeback. According to the Centers for Disease Control, more than two million people come down with antibiotic-resistant infections annually, and at least 23,000 die because their treatment can't stop the infection. In addition, the pipeline for new antibiotics has grown dangerously thin.
http://www.worldpharmanews.com/research/2709-scientists-find-resistance-mechanism-that-could-impact-antibiotic-drug-development